Searchable abstracts of presentations at key conferences in endocrinology

ea0013p155 | Diabetes, metabolism and cardiovascular | SFEBES2007

Sodium valproate monotherapy increases ovarian hyperandrogenism but does not affect arterial compliance in young women with epilepsy

Rice Sam , Agarwal Neera , Bolusani Hemanth , Scanlon Maurice , Pierri Melissa , Smith Phil , Rees Aled

Background: Women with epilepsy may be at risk of developing PCOS, but it is unclear whether this is due to the disease or sodium valproate (VPA) therapy. We sought to determine androgenic status and cardiometabolic risk in women taking VPA monotherapy and compared these with subjects taking lamotrigine and healthy controls.Methods: Patients with epilepsy (age 18–43) with no known vascular risk were divided into 3 groups: VPA monotherapy (n=1...